Yes, there are different default fonts used in Safari, Chrome, Edge, Opera, & Firefox. You might have a preference for a particular monospace fixed-width font or even Serif (Times New Roman) and Sans-serif fonts (Arial)? I personally like Consolas for a fixed-width font, but another default often used is Courier New.
In OpenRefine, any text input or text display dialogs mostly are setup to display with a monospace fixed-width font:
font-family: monospace;
facets.css code
So in Safari, you might click on Preferences -> Fonts & Colors and change them to your liking, or in Chrome.